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My progress through my weight-loss journey. These are the results of my progress from taking the weight management system which includes Max Switch and Be Bars! For more information go to www.max.com/643069 or inbox!

Glutathione and Meniere’s: Meniere's disease is a disorder of the inner ear that causes spontaneous episodes of vertigo a sensation of a spinning motion along with fluctuating hearing loss, ringing in the ear (tinnitus), and sometimes a feeling of fullness or pressure in your ear. Although the cause is unknown, oxidative stress plays a role. A significant decrease in both plasma and lymphocyte ratio reduced glutathione (GSH) vs. oxidized glutathione (GSSG) was observed.... Patients were divided into three groups (control, conventional therapy, and antioxidant treatment), and those in the antioxidant treatment group, especially those with Ménière's syndrome, demonstrated a net and more significant improvement. Several scientific papers show that increased oxidative stress due to production of excessive amounts of free radicals derived from oxygen and nitrogen, and acute and/or chronic inflammation produced by diverse groups of agents such as high intensity noise, vibration, cisplatin, gentamicin, aging, and Meniere’s diseaseare major factors in the initiation and progression of hearing disorders. Besides well-characterized antioxidantssuch as vitamin A, carotenoids, vitamin C, and vitamin Eother antioxidants are also important in protecting against cellular damage in the ear, including coenzyme and glutathione. However, oral supplementation with glutathione failed to significantly increase plasma levels of glutathione in human subjects, suggesting that this tripeptide is completely hydrolyzed in the gastrointestinal (GI) tract. [That’s why RiboCeine and supporters of the antioxidant defense system are so important.] Oxidative stress, redox homeostasis and cellular stress response in Ménière's disease: role of vitagenes. http://www.ncbi.nlm.nih.gov/pubmed/21042850 The role of free radicals and plasmatic antioxidant in Ménière's syndrome. http://www.ncbi.nlm.nih.gov/pubmed/15106283 Radical scavengers for Ménière's disease after failure of conventional therapy: a pilot study. http://www.ncbi.nlm.nih.gov/pubmed/12953767 The Case for Using Multiple Antioxidants in Hearing Disorders http://www.hearingreview.com//the-case-for-using-multiple/ A combination antioxidant therapy prevents age-related hearing loss in C57BL/6 mice. http://www.ncbi.nlm.nih.gov/pubmed/20723783 For more info go to www.max.com/643069 or inbox!

Glutathione and Chemobrain: For years, cancer patients have complained about a phenomenon known as chemobrain, or chemotherapy-associated cognitive dysfunction. Chemobrain is characterized by memory, concentration, and attention problems, including a general feeling of mental fogginess. Because chemotherapy does not pass the blood-brain barrier, these complaints were initially dismissed. As the number of cancer survivors reporting this phenomenon has grown, so too has the ...body of research. Inflammation, oxidative stress, toxicity, and low brain levels of GSH are implicated in cognitive dysfunction. Chemotherapy can improve prospects for long-term survival after a cancer diagnosis, but it may also be associated with long-term toxicity, including the possibility of cognitive dysfunction. Now, more sophisticated imaging methods and animal models have begun to show evidence of brain changes associated with cancer and to suggest mechanisms that could make chemotherapy one of the culprits. A loss of GSH can impact cognitive function. Decreases in GSH are also associated with microglial activation and endothelial dysfunction, both of which can contribute to impairments in brain function. Glutathione elevation by gamma-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain. http://www.ncbi.nlm.nih.gov/pubmed/17171703 Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain. [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852883/ Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain. http://www.ncbi.nlm.nih.gov/pubmed/16298740 Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy. http://www.ncbi.nlm.nih.gov/pubmed/25573802 An Overview of Chemotherapy-Related Cognitive Dysfunction, or ‘Chemobrain’ [Free Full Text] http://www.cancernetwork.com//overview-chemotherapy-relate Treating Chemobrain: Rehabilitation Therapies Emerge http://jnci.oxfordjournals.org/content/104/22/1691.long Functional consequences of age-dependent changes in glutathione status in the brain. http://www.ncbi.nlm.nih.gov/pubmed/23249101 Glutathione redox imbalance in brain disorders. http://www.ncbi.nlm.nih.gov/pubmed/25405315 Chemo Brain http://www.cancer.org//phy/chemotherapyeffects/chemo-brain For more info go to www.max.com/643069 or inbox!

Glutathione and Mitochondria: Mitochondria are the energy stations of the cell- they produce ATP, which is the cellular currency for energy. ATP is used for metabolism, biosynthesis, motility, and cell division. ATP is also important in cell signaling and in DNA/RNA synthesis. Keeping mitochondria in good shape is essential for health and energy. The problem is, mitochondria are highly susceptible to oxidative damage. Dr Terry Wahls states, "Mitochondria require plenty of a...ntioxidants, which protect them from the free radicals generated during the production of ATP." The master "skeleton key" antioxidant, glutathione, is critical to the condition of mitochondria. Mitochondrial glutathione depletion is implicated in both alcoholic and non-alcoholic liver diseases as well as neurological diseases such as Alzheimer's and Parkinson's. Muscle cells are packed with mitochondria, so strength and athletic performance depend on ATP and glutathione as well. You can't just take ATP or glutathione, though. Your cells have to make them. Providing the right 'ingredients' is key. This video provides a great explanation: The Powerhouse of the Cell - PBS LearningMedia http://www.pbslearningmedia.org//the-powerhouse-of-the-ce/ Mitochondrial Glutathione: features, regulation and role in disease. [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578987/ Mitochondrial Glutathione, a Key Survival Antioxidant [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821140/ Glutathione and mitochondria [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079069/ Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics http://www.cell.com//bioche/abstract/S0968-0004(13)00156-4 Curcumin reduces oxidative damage by increasing reduced glutathione and preventing membrane permeability transition in isolated brain mitochondria. http://www.ncbi.nlm.nih.gov/pubmed/24461330 Why Taking Care Of Your Mitochondria Might Be The Key To Health & Vitality http://www.mindbodygreen.com//why-taking-care-of-your-mito "When people suffering from fatigue appear in my clinic, I often find that the root cause of their fatigue is poor functioning of their mitochondria. To reverse the fatigue and feel better, these patients need a mitochondrial tuneup." For more info go to www.max.com/643069 or inbox!

Glutathione and Dental Health: As the master antioxidant, Glutathione is the most important redox regulator that controls inflammatory processes, including the inflammation that occurs in the mouth and around the teeth (the periodontium). Patients with periodontitis (gum infection) have lower antioxidant and reduced glutathione status. Proper oral hygiene is certainly important, but so too is supporting the internal glutathione system. The implications of dental health and i...ts connection with a variety of conditions is far-reaching. The antioxidant master glutathione and periodontal health [free full text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630702/ Evaluation of non-surgical therapy on glutathione levels in chronic periodontitis [free full text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569996/ Oxidative stress markers in saliva and periodontal disease status: modulation during pregnancy and postpartum [free full text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495776/ Comparison of salivary antioxidant enzyme activity between ex-smokers and subjects who had never smoked. http://www.ncbi.nlm.nih.gov/pubmed/25864765 Oxidative Stress: A Link between Diabetes Mellitus and Periodontal Disease [free full text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265692/ For more info go to www.max.com/643069 or inbox!

Glutathione and Sleep Beauty rest, anyone? When you sleep, *you're* out cold, but your brain is a busy busy bee. That first one, Brain Drain? He's referring to the glymphatic system, managed by glial cells. Glial cells and the neurons they protect rely heavily on glutathione not only for defense against excess reactive oxygen species, but also as the "soap" that binds to molecules that the brain wants to wash away. No wonder then, given this waste management system, that man...y people who boost their cells' ability to produce glutathione report better sleep- they sleep soundly, and some recall more vivid dreams. Scientists Discover Previously Unknown Cleansing System in Brain https://www.urmc.rochester.edu//scientists-discover-previo Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress http://www.jneurosci.org/content/23/8/3394.full.pdf For more information go to www.max.com/643069 or inbox!

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For more information on how you can make your dreams come true as well go to www.max.com/643069 or inbox!

My progress through my weight-loss journey. These are the results of my progress from taking the weight management system which includes Max Switch and Be Bars! For more information go to www.max.com/643069 or inbox!

Glutathione and Meniere’s: Meniere's disease is a disorder of the inner ear that causes spontaneous episodes of vertigo a sensation of a spinning motion along with fluctuating hearing loss, ringing in the ear (tinnitus), and sometimes a feeling of fullness or pressure in your ear. Although the cause is unknown, oxidative stress plays a role. A significant decrease in both plasma and lymphocyte ratio reduced glutathione (GSH) vs. oxidized glutathione (GSSG) was observed.... Patients were divided into three groups (control, conventional therapy, and antioxidant treatment), and those in the antioxidant treatment group, especially those with Ménière's syndrome, demonstrated a net and more significant improvement. Several scientific papers show that increased oxidative stress due to production of excessive amounts of free radicals derived from oxygen and nitrogen, and acute and/or chronic inflammation produced by diverse groups of agents such as high intensity noise, vibration, cisplatin, gentamicin, aging, and Meniere’s diseaseare major factors in the initiation and progression of hearing disorders. Besides well-characterized antioxidantssuch as vitamin A, carotenoids, vitamin C, and vitamin Eother antioxidants are also important in protecting against cellular damage in the ear, including coenzyme and glutathione. However, oral supplementation with glutathione failed to significantly increase plasma levels of glutathione in human subjects, suggesting that this tripeptide is completely hydrolyzed in the gastrointestinal (GI) tract. [That’s why RiboCeine and supporters of the antioxidant defense system are so important.] Oxidative stress, redox homeostasis and cellular stress response in Ménière's disease: role of vitagenes. http://www.ncbi.nlm.nih.gov/pubmed/21042850 The role of free radicals and plasmatic antioxidant in Ménière's syndrome. http://www.ncbi.nlm.nih.gov/pubmed/15106283 Radical scavengers for Ménière's disease after failure of conventional therapy: a pilot study. http://www.ncbi.nlm.nih.gov/pubmed/12953767 The Case for Using Multiple Antioxidants in Hearing Disorders http://www.hearingreview.com//the-case-for-using-multiple/ A combination antioxidant therapy prevents age-related hearing loss in C57BL/6 mice. http://www.ncbi.nlm.nih.gov/pubmed/20723783 For more info go to www.max.com/643069 or inbox!

Glutathione and Chemobrain: For years, cancer patients have complained about a phenomenon known as chemobrain, or chemotherapy-associated cognitive dysfunction. Chemobrain is characterized by memory, concentration, and attention problems, including a general feeling of mental fogginess. Because chemotherapy does not pass the blood-brain barrier, these complaints were initially dismissed. As the number of cancer survivors reporting this phenomenon has grown, so too has the ...body of research. Inflammation, oxidative stress, toxicity, and low brain levels of GSH are implicated in cognitive dysfunction. Chemotherapy can improve prospects for long-term survival after a cancer diagnosis, but it may also be associated with long-term toxicity, including the possibility of cognitive dysfunction. Now, more sophisticated imaging methods and animal models have begun to show evidence of brain changes associated with cancer and to suggest mechanisms that could make chemotherapy one of the culprits. A loss of GSH can impact cognitive function. Decreases in GSH are also associated with microglial activation and endothelial dysfunction, both of which can contribute to impairments in brain function. Glutathione elevation by gamma-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain. http://www.ncbi.nlm.nih.gov/pubmed/17171703 Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain. [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852883/ Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain. http://www.ncbi.nlm.nih.gov/pubmed/16298740 Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy. http://www.ncbi.nlm.nih.gov/pubmed/25573802 An Overview of Chemotherapy-Related Cognitive Dysfunction, or ‘Chemobrain’ [Free Full Text] http://www.cancernetwork.com//overview-chemotherapy-relate Treating Chemobrain: Rehabilitation Therapies Emerge http://jnci.oxfordjournals.org/content/104/22/1691.long Functional consequences of age-dependent changes in glutathione status in the brain. http://www.ncbi.nlm.nih.gov/pubmed/23249101 Glutathione redox imbalance in brain disorders. http://www.ncbi.nlm.nih.gov/pubmed/25405315 Chemo Brain http://www.cancer.org//phy/chemotherapyeffects/chemo-brain For more info go to www.max.com/643069 or inbox!

Glutathione and Mitochondria: Mitochondria are the energy stations of the cell- they produce ATP, which is the cellular currency for energy. ATP is used for metabolism, biosynthesis, motility, and cell division. ATP is also important in cell signaling and in DNA/RNA synthesis. Keeping mitochondria in good shape is essential for health and energy. The problem is, mitochondria are highly susceptible to oxidative damage. Dr Terry Wahls states, "Mitochondria require plenty of a...ntioxidants, which protect them from the free radicals generated during the production of ATP." The master "skeleton key" antioxidant, glutathione, is critical to the condition of mitochondria. Mitochondrial glutathione depletion is implicated in both alcoholic and non-alcoholic liver diseases as well as neurological diseases such as Alzheimer's and Parkinson's. Muscle cells are packed with mitochondria, so strength and athletic performance depend on ATP and glutathione as well. You can't just take ATP or glutathione, though. Your cells have to make them. Providing the right 'ingredients' is key. This video provides a great explanation: The Powerhouse of the Cell - PBS LearningMedia http://www.pbslearningmedia.org//the-powerhouse-of-the-ce/ Mitochondrial Glutathione: features, regulation and role in disease. [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578987/ Mitochondrial Glutathione, a Key Survival Antioxidant [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821140/ Glutathione and mitochondria [Free Full Text] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079069/ Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics http://www.cell.com//bioche/abstract/S0968-0004(13)00156-4 Curcumin reduces oxidative damage by increasing reduced glutathione and preventing membrane permeability transition in isolated brain mitochondria. http://www.ncbi.nlm.nih.gov/pubmed/24461330 Why Taking Care Of Your Mitochondria Might Be The Key To Health & Vitality http://www.mindbodygreen.com//why-taking-care-of-your-mito "When people suffering from fatigue appear in my clinic, I often find that the root cause of their fatigue is poor functioning of their mitochondria. To reverse the fatigue and feel better, these patients need a mitochondrial tuneup." For more info go to www.max.com/643069 or inbox!